Pathogen reduction of whole blood: utility and feasibility

Pathogen Reduction of Plasma

Pathogen Reduction Technology Treatment of Platelets, Plasma and Whole Blood Using Riboflavin and UV Light.

Bacterial contamination and emerging infections combined with increased international travel pose a great risk to the safety of the blood supply. Tests to detect the presence of infection in a donor have a 'window period' during which infections cannot be detected but the donor may be infectious. Agents and their transmission routes need to be recognized before specific tests can be developed. ...

Whole blood pathogen reduction technology and blood safety in sub-Saharan Africa: A systematic review with regional discussion

BACKGROUND Despite vast improvements in transfusion services in sub-Saharan Africa over the last decade, there remain serious concerns on the safety and adequacy of the blood supply across the region. OBJECTIVE This review paper ascertains the role of pathogen reduction technology (PRT) in improving blood safety and supply adequacy in the region. METHOD The state of blood safety in sub-Saha...

pathogen reduction of plasma

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Introducing Pathogen Reduction Technology in Poland: A Cost-Utility Analysis.

BACKGROUND Mirasol® pathogen reduction technology (PRT) uses UV light and riboflavin to chemically inactivate pathogens and white blood cells in blood components. In the EU, Mirasol PRT is CE-marked for both plasma and platelet treatment. In Poland, the decision to introduce PRT treatment of the national supply of fresh frozen plasma has spurred interest in evaluating the cost-effectiveness of ...